Generalized Epilepsy and Febrile Seizures Syndrome
نویسندگان
چکیده
منابع مشابه
Melatonin’s Effect in Febrile Seizures and Epilepsy
OBJECTIVE Recognition of risk factors for febrile seizures (FS) and epilepsy is essential. Studies regarding the role of melatonin in these convulsive disorders are limited. This study determines the relationship between serum melatonin levels and FS and epilepsy in children. MATERIALS & METHODS A population of 111 children with simple FS, complex FS, and epilepsy (37 children per group, resp...
متن کاملGeneralized epilepsy with febrile seizures plus. A genetic disorder with heterogeneous clinical phenotypes.
The clinical and genetic relationships of febrile seizures and the generalized epilepsies are poorly understood. We ascertained a family with genealogical information in 2000 individuals where there was an unusual concentration of individuals with febrile seizures and generalized epilepsy in one part of the pedigree. We first clarified complex consanguineous relationships in earlier generations...
متن کاملEpidemiology of febrile seizures and epilepsy: a call for action.
Seizures triggered by fever, qualified as febrile seizures, have been for decades a major issue for children in developed countries and more so in resource-limited settings. Approximately 2--5% of children are affected by this kind of seizure. Many studies aimed to describe, measure, and analyze several hypotheses, including the assessment of the physiopathological mechanisms, epidemiological i...
متن کاملA novel locus for generalized epilepsy with febrile seizures plus in French families.
BACKGROUND Generalized epilepsy with febrile seizures plus (GEFS(+)) is a familial autosomal dominant entity characterized by the association of febrile and afebrile seizures. Mutations in 3 genes--the sodium channel alpha1 subunit gene (SCN1A), the sodium channel beta1 subunit gene (SCN1B), and the gamma2 GABA receptor subunit gene (GABRG2)--and linkage to 2 other loci on 2p24 and 21q22 have b...
متن کاملGeneralized epilepsy with febrile seizures plus: further heterogeneity in a large family.
BACKGROUND Generalized epilepsy with febrile seizures plus (GEFS(+)) is a recently described benign childhood-onset epileptic syndrome with autosomal dominant inheritance. The most common phenotypes are febrile seizures (FS) often with accessory afebrile generalized tonic-clonic seizures (GTCS, FS(+)). In about one third, additional seizure types occur, such as absences, myoclonic, or atonic se...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1999
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-13-1-1